It is indeed interesting given how much is known in biochemistry how little of clinical value exists for Alzheimer's et al. As far as I can see, effectively no

It is indeed interesting given how much is known in biochemistry how little of clinical value exists for Alzheimer's et al. As far as I can see, effectively nothing useful regarding treatment exists. One interesting thing i've got from talking to specialists in the area and from some research is that a genetic inherited component is not particularly considered in a clinical setting. My family on my maternal side has extremely reliably strong expression of Alzheimer's type disease (including visual hallucination etc) from age 70/71 to the point it hits like clockwork. My mother being of 10 brothers and sisters some who lived normally, some who lived "well" (i.e.) very good diets, no alcohol, lots of exercise and it hit them like clockwork as they aged no matter lifestyle choices. Families like that are a good candidate for research There are some efforts to identify the apparent significant minority of deterministic Alzheimer's [1] and to clinically trial things that e.g. asymptomatic amyloid beta build up prophylactic treatment. But APP/PS/APOE genes were identified in the 1980s and 1990s and we don't seem any closer to clinical results. You go to a specialist in the NHS in the UK today and you will get a comforting grimace followed by a torturous inefficient bureaucracy through which you must prevail to get care services for the inevitable decline. [1] https://dian.wustl.edu/ https://dian.wustl.edu/ [2] https://en.wikipedia.org/wiki/Amyloid_beta https://en.wikipedia.org/wiki/Amyloid_beta