Not all changes are equal. One thing is to, say, patch a known disease-causing mutation (being sure no other changes take place). Inserting a new sequence or pa

Not all changes are equal. One thing is to, say, patch a known disease-causing mutation (being sure no other changes take place). Inserting a new sequence or patching an existing sequence in a way not seen before is clearly different. Another important dimension is whether the introduced changes are heritable and would be passed to offsprings.