2 ms·
In a later paper (2021) they tried the same experiment in mice: the paper claim that together with neocortex expansion, the behaviour of mice was altered( highe
by Neeklo 4y ago
In a later paper (2021) they tried the same experiment in mice: the paper claim that together with neocortex expansion, the behaviour of mice was altered( higher memory flexibility and reduced anxiety levels). This is still not what you're asking but quite interesting in my opinion!
To get to your question (to which I really don't know the answer!): from my understanding, the mechanisms through wigh arhgap11b works are still not clear, so the simple overexpression might not be the answer for mega-brains! (sometimes these genes are regulated upstream so you cannot force them really, or on the other end, overexpression of genes often brings other unwanted consequences)
- daniel-cussen 4y agoYeah but more energy use, and further they were better at the challenges set so far, no the challenges to come as the experimenters adapted to the change.
- sinenomine 4y ago> the behaviour of mice was altered( higher memory flexibility and reduced anxiety levels). Notably, this isn't the first time there was a success in murine cognitive enhancement via genetic engineering. There was a promising line of research targeting NR2B overexpression: [1][2]. There seems to be an unfortunate lack of funding and research in this area. 1. https://www.nature.com/articles/43432 https://www.nature.com/articles/43432 2. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007486 https://journals.plos.org/plosone/article?id=10.1371/journal...