You gave no way of "guesstimating" how bad/good the signal is and how easy it is to improve detecting it once you start working on it. Maybe cell do quire often

You gave no way of "guesstimating" how bad/good the signal is and how easy it is to improve detecting it once you start working on it. Maybe cell do quire often leak more DNA than you'd expect, maybe there's some drug or phisical-activity people can do before testing to temporarily increase overall cell damage and DNA leakage etc. Don't assume your gut feeling correlates with reality in such a quantitative problem. There might be low hanging fruit here - and it might save your freakin life man! Biochemical testing is not intuitive and the details are best lead to quantitative biochemists and such. Heck, even what Theranos embarked on doing could've lead to breakthrough improvements for some tests if they had been honest and focused the money on the research avenues that could've produced results...