NetBSD has nvmm. Qemu is quite fast as as result. I run many distros ontop of it. Plus Xen. My laptop has been running Xen with pv instances for app isolation.

NetBSD has nvmm. Qemu is quite fast as as result. I run many distros ontop of it. Plus Xen. My laptop has been running Xen with pv instances for app isolation. Never as fancy as Qubes though.