There will always be a dependency on resources or products from other countries - especially if we truly respect the rights of self-determination of arbitrarily

There will always be a dependency on resources or products from other countries - especially if we truly respect the rights of self-determination of arbitrarily small nations and city-states. True sovereignty of these states also means that they have the right to not trade with us for any reason, does it not? There will also always be disagreements on fundamental ethical issues between countries. Even between the states in the US you can see such disagreements. What we seem to lack is a principle for dealing with such situations. Instead, ad-hoc, inconsistent measures tend to be taken. It seems like if the true principle guiding such decisions were publicly announced, the general public would find it unpalatable. Are we living in willful denial? Can such a principle then exist, that would both be consistent with our declared values, without compromising our ability to survive and defend ourselves and act according to it?