I don't honestly think that anyone has been put at misery. At best we will have taken slightly longer for a cure (or maybe we'll never find one). I feel like

I don't honestly think that anyone has been put at misery. At best we will have taken slightly longer for a cure (or maybe we'll never find one). I feel like there area few too many ethical gymnastics you have to do to blame overzealous scientists for chasing down the wrong rabbit hole. But, yes the trait in general of blinded belief (versus belief used to drive effort and focus but with self-awareness that it's just a tool) among some scientists feels uncouth. I am lucky to not have had to deal with that personally. I did see it in some neighboring labs, some of those grad students got utterly fucked and when they presented consolation thesis defenses for seven years of misery, they had the dazed look like someone who had just escaped an underground cult to see the sunlight finally. You're right not all of them are antibodies, but the ones that aren't might not be working for "other reasons". Yes, that is a cheap way out, but I still think it's worth trying (and I don't generally believe in the amyloid hypothesis) I'm surprised IgG isn't degraded by insulin-degrading enzyme.