Very common, no doubt. Targeting GPCRs is a very wide net, GPCRs are a huge superfamily of proteins. > GPCRs are an important drug target and approximately 3

Very common, no doubt. Targeting GPCRs is a very wide net, GPCRs are a huge superfamily of proteins. > GPCRs are an important drug target and approximately 34%[6] of all Food and Drug Administration (FDA) approved drugs target 108 members of this family. The global sales volume for these drugs is estimated to be 180 billion US dollars as of 2018.[6] It is estimated that GPCRs are targets for about 50% of drugs currently on the market, mainly due to their involvement in signaling pathways related to many diseases i.e. mental, metabolic including endocrinological disorders, immunological including viral infections, cardiovascular, inflammatory, senses disorders, and cancer. The long ago discovered association between GPCRs and many endogenous and exogenous substances, resulting in e.g. analgesia, is another dynamically developing field of the pharmaceutical research.[2]