This is a very good point. Also, in my case, I know that there are some things I'd like to do that are almost impossible to do when you're small or it would be

This is a very good point. Also, in my case, I know that there are some things I'd like to do that are almost impossible to do when you're small or it would be a complete waste to reinvent the wheel. Some biggies already have the technology I'd need to get closer to my dream, so I think the ideal path is to keep developing and getting a high profile in a niche that is under the radar and not easily replicable, and scope out potential buyers, not just by money offered but by product/vision fit. In short, it's a mental thing, not what happens on contract paper, that counts.