It’s not just the nicotine; rather, nicotine is a weak and essentially non-reinforcing stimulant unless it is administered with monoamine oxidase inhibitors, su

It’s not just the nicotine; rather, nicotine is a weak and essentially non-reinforcing stimulant unless it is administered with monoamine oxidase inhibitors, such as those found in tobacco smoke and coffee, which greatly potentiate nicotine’s effects and make it strongly reinforcing.