3 ms·
Is there research to engineer ways so that we can use blood as delivery only in some areas ? I know it sounds stupid but maybe toying with timings so that chemi
by agumonkey 4y ago
Is there research to engineer ways so that we can use blood as delivery only in some areas ? I know it sounds stupid but maybe toying with timings so that chemicals never live long enough to reach upper body / brain ? or maybe microcapsules that only dissolve in certain biological environment ?
- db65edfc7996 4y agoSpecifically targeting compounds is an active area of research. Example: all oncotherapies are essentially just poison. The trick is to deliver the toxin to the 0.001% of cells in the body that are cancerous. It is amusing you should say ways that avoid reaching the brain. The blood-brain barrier impedes a large number of therapeutics from entering the brain. It is incredibly difficult to engineer the constraints of something that: is potent enough to have an effect, can survive in the blood, cross into the brain, targets the cells of interest, has a meaningful half-life, does not decompose into something toxic, etc.