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This is happening around the world. Any vaccine doses seems to be more protective than no vaccine doses, but, after a few months from latest dose, the fewer (b
by codefreeordie 4y ago
This is happening around the world. Any vaccine doses seems to be more protective than no vaccine doses, but, after a few months from latest dose, the fewer (but nonzero) doses you have, the less likely you are to get sick, be hospitalized, or die.
- azth 4y agoThat's interesting. Do you have the rationale for why that is the case? What about recovered individuals?
- codefreeordie 4y agoIt's still unclear exactly why that's the case, but it keeps turning up unlooked-for in different datasets (including from different jurisdictions which use different methodologies) So far, the most promising theories involve new variants exploiting the immune effects of repeated exposure to the original spike proteins. In particular, the South African and Portuguese datasets on BA.4 and BA.5 lend themselves to this explanation -- but even with older variants, like BA.2/Omicron, the graphs just keep pointing in this direction. It seems that about 4-6ish months after boost, you're worse off than you were pre-boost.
- lamontcg 4y ago> The new data do not mean booster shots are somehow increasing the risk. Ongoing studies continue to provide strong evidence of additional protection offered by booster shots against infection, severe disease, and death. https://www.cbsnews.com/news/covid-19-vaccine-booster-shot-infection-rate/ https://www.cbsnews.com/news/covid-19-vaccine-booster-shot-i... So, more shots is more protective against severe disease. The higher rate of infection right now is likely to due this cohort being the last to get exposed to the virus, because they were taking precautions all along. Vaccines in your arm don't give you sterilizing mucosal immunity in your nose (even assuming that exists for this virus at all).