3 ms·

> Complete tolerance to caffeine's subjective effects is complete and takes at least 2 weeks at 400mg/day to develop. Caffeine's performance-enhancing effects r

> Complete tolerance to caffeine's subjective effects is complete and takes at least 2 weeks at 400mg/day to develop. Caffeine's performance-enhancing effects remain for at least 20 days at 210mg/day. Tolerance to caffeine's effects on cerebral blood flow, blood pressure, and cortisol is incomplete. Tolerance takes 2 days to reverse at 100mg/day and up to 9+ days at 400mg+/day. So... 2 weeks on, 2 weeks off?

jmpman 4y ago
As with all drugs, it’s more fun to abuse them then simply use them.
Tenoke 4y ago
Being in withdrawal so often sounds worse than just taking it daily with occasional short breaks to reset a bit.