It generally has bigger file sizes (uses PNG24 instead of PNG8), but OTOH it can handle gradient-full true-color images beyond what PNG8 can. You can combine b

It generally has bigger file sizes (uses PNG24 instead of PNG8), but OTOH it can handle gradient-full true-color images beyond what PNG8 can. You can combine both: use pngquant with quality limit to get the best file size where possible, and pngloss as a fallback to still compress other types of images.