See DEC's FX!32 (running x86 WinNT 3.51 binaries on WinNT 3.51 workstations with Alpha AXP CPUs) and HP's Project Dynamo. There are probably even earlier examp

See DEC's FX!32 (running x86 WinNT 3.51 binaries on WinNT 3.51 workstations with Alpha AXP CPUs) and HP's Project Dynamo. There are probably even earlier examples, but FX!32 was roughly equivalent to Rosetta, and shipping production code in the 1990s.