5 ms·
For leukemia, there are a lot of promising new treatments and clinical trials. For metastatic solid-state tumors, much less. We're still in the dark ages of can
by adamredwoods 4y ago
For leukemia, there are a lot of promising new treatments and clinical trials. For metastatic solid-state tumors, much less. We're still in the dark ages of cancer treatment.
- axpy906 4y agoWhat treatments in particular?
- adamredwoods 4y agoCar-T seems promising for leukemia and lymphoma, but not as efficacious in solid tumors: https://www.lls.org/treatment/types-treatment/immunotherapy/chimeric-antigen-receptor-car-t-cell-therapy https://www.lls.org/treatment/types-treatment/immunotherapy/... Also 2nd gen BTK inhibitors: https://en.wikipedia.org/wiki/Acalabrutinib https://en.wikipedia.org/wiki/Acalabrutinib https://en.wikipedia.org/wiki/Bruton%27s_tyrosine_kinase https://en.wikipedia.org/wiki/Bruton%27s_tyrosine_kinase
- elhudy 4y agoBTK inhibitors are technically in 3rd gen (noncovalent) already if you can get in the trials (which are very promising considering they use the same mechanism).
- gjreda 4y agoImatinib (Gleevac) revolutionized treatment for patients with chronic myeloid leukemia (CML). Prior to the drug’s discovery, CML patients generally had seven years to live (possibly less depending on how advanced the cancer was). Now their lifespan mirrors the general population. I’d highly recommend the book The Philadelphia Chromosome if you’re interested in learning more.
- macdaknife 4y agoI am currently taking a similar drug for Myelofibrosis on a clinical trial holed up after a stem cell transplant here at MD Anderson Cancer Center. It's called Itacitinib, and is supposed to prevent GVHD. It's by the same company that makes Jakafi (brand name). These are expensive drugs for sure, and my DR is running the clinical trial. Just wanted to chime in from the inside. ;p
- moneywoes 4y agoBest of luck for your treatment
- robocat 4y agoFYI: your comment is a unique result for “metastatic solid-state tumors”[1], so much much less? [1] https://www.google.co.nz/search?q=%22metastatic+solid-state+tumors%22&tbs=li:1 https://www.google.co.nz/search?q=%22metastatic+solid-state+...
- DarylZero 4y agoWe talking tumors in the state of metastatic solid?
- SnowHill9902 4y agoI think he means just solid in the sense that it’s not moving cells.
- lmeyerov 4y agoI think the usual split of solid tumor vs blood (aka 'hematologic' or 'heme')
- WheatM 4y ago
- beefman 4y agoThe "-state" part is the neologism. GP meant "solid tumors" or "solid cancers".