3 ms·
I went down this rabbit hole a little. It does seem like the specific formulation of AKG may matter. The commonly available supplements are L-Orthinine Alpha-Ke
by yojo 4y ago
I went down this rabbit hole a little. It does seem like the specific formulation of AKG may matter. The commonly available supplements are L-Orthinine Alpha-Ketogluterate (OKG) and Arginine-Alpha-Ketoglutarate (AAKG).
The study in question used Calcium Alpha-Ketoglutarate (CAAKG).
There are a few sellers of CAAKG, but it is an order of magnitude more expensive than the others. (~$1.50/gram for CAAKG vs ~$.08/gram for OKG and ~$.05/gram for AAKG)
There have been studies in the past (for non-aging conditions) that have demonstrated a difference between OKG and AAKG, so it's reasonable to assume there may be a difference between CAAKG and the others as well. Without a study, who knows.
Also as other commenters have mentioned, the only evidence so far for aging related benefits is in mice. Of the human trial studies I could find for OKG use, it does seem like there were no reported side effects, so it might not hurt you, but it also might not do anything for you.