Ask YC: Boston or Bay Area?

I have just been offered a position in Boston. Current I live and work in the south Bay Area. It's an equivalent position, so not a jump in the career ladder, but to an industry I'm really interested in and a really great company. I'd be getting a lot less equity though. Has anyone here done the east coast/west coast relocation? What's it like? Any transitional issues? Any suggestions for one city over the other?