> The biggest outbreak of monkeypox in the U.S. occurred in 2003, when health authorities found 47 confirmed and probable cases in six states — Illinois, Indian

> The biggest outbreak of monkeypox in the U.S. occurred in 2003, when health authorities found 47 confirmed and probable cases in six states — Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin. “All people infected with monkeypox in this outbreak became ill after having contact with pet prairie dogs. The pets were infected after being housed near imported small mammals from Ghana. This was the first time that human monkeypox was reported outside of Africa.” During this outbreak, 28 adults and two children were given the smallpox vaccine and “no serious adverse events were reported.” Not only did this outbreak not turn into a major public-health crisis, it barely made the national news. When the New York Times wrote about it back in June 2003, the story ran on page A20. Emphasis added, source: https://www.nationalreview.com/the-morning-jolt/what-you-need-to-know-about-monkeypox/ https://www.nationalreview.com/the-morning-jolt/what-you-nee... With some exceptions the youngest people who received the smallpox vaccine in America are now 50, so it’s possible that we’ll see more monkeypox cases than previously (the smallpox vaccine provides 85% protection). We were able to eradicate smallpox completely because it has no animal reservoir, unlike monkeypox which also infects rodents and monkeys.