The CDC claims that the US Strategic National Stockpile holds enough smallpox vaccine to inoculate every person in the US: https://www.cdc.gov/smallpox/bioterro

The CDC claims that the US Strategic National Stockpile holds enough smallpox vaccine to inoculate every person in the US: https://www.cdc.gov/smallpox/bioterrorism-response-planning/public-health/vaccination-strategies.html https://www.cdc.gov/smallpox/bioterrorism-response-planning/... > The Strategic National Stockpile (SNS) has stockpiled enough smallpox vaccine to vaccinate every person in the United States. In a smallpox emergency, the SNS will coordinate with the Medical Countermeasures (MCM) coordinator or the preparedness office in the state or territorial health department. The MCM coordinator will allocate vaccine to local areas, depending upon the circumstances of the emergency. How long that would take to roll out is anyone's guess, but I believe a vaccination campaign could rollout fairly quickly if the monkeypox outbreak turns out to be sufficiently contagious to warrant use of the reserve, assuming the reserve is effective against any possible mutations.