You're kind of asking two questions in one: PHP or Python? and Framework or homebrew? If you switch from PHP to Python and things don't work out, you'll blame

You're kind of asking two questions in one: PHP or Python? and Framework or homebrew? If you switch from PHP to Python and things don't work out, you'll blame Python. I'd stick with PHP. If you use a framework and it doesn't work out you can just code away from the framework. I'd go with Zend Framework. It takes some effort to learn the router stuff, but never seeing another url that ends with .php is worth it on it's own. Good luck!