Time resolved protein crystallography is a technique that achieves what you’re looking for. https://en.wikipedia.org/wiki/Time_resolved_crystallography https:/

Time resolved protein crystallography is a technique that achieves what you’re looking for. https://en.wikipedia.org/wiki/Time_resolved_crystallography https://en.wikipedia.org/wiki/Time_resolved_crystallography https://youtu.be/wqYMA2rh8ow https://youtu.be/wqYMA2rh8ow https://youtu.be/OFnVsdFXifg https://youtu.be/OFnVsdFXifg By the way, around 50% of the volume in protein crystals is usually occupied by water, with some cases reaching up to 80%.