3 ms·
Cross-reactivity between myelin-sensitive antibodies and EB-sensitive antibodies seen in 25% of cases, according to the study itself. Very much overblown. Much
by Khelavaster 4y ago
Cross-reactivity between myelin-sensitive antibodies and EB-sensitive antibodies seen in 25% of cases, according to the study itself. Very much overblown.
Much more likely that imbalances in cells with entry points for infection, CD21 (Epstein-Barr virus receptor) and CD35 (complement receptor 1), are to blame. Including B cells, some T cells, red blood cells, and others.
- panabee 4y agoThanks for commenting. Are you suggesting 25% is insignificant, or simply insufficient to claim causation? What threshold would be meaningful in your opinion? To clarify, the researchers believe 25% is a conservative estimate.
- Khelavaster 4y agoInsufficient to claim causation. If it isn't detectable in 75% of MS patients, it's probably not the cause of MS..
- zosima 4y agoI disagree: 1. All cases of MS does not have to be caused by similar antibodies. 2. MS usually progresses through attacks. Antibody may only be present when an MS attack occurs.
- Khelavaster 4y ago1. The mechanism of MS, including antibodies, isn't quite the same as the "cause". 2. "Memory" antibodies need to be present to keep immunity.