3 ms·
You Mom's story is so sad and it is why I do not go to doctors anymore. My mother probably had lupus as well that went undiagnosed her hole life. We have all th
by FollowingTheDao 4y ago
You Mom's story is so sad and it is why I do not go to doctors anymore. My mother probably had lupus as well that went undiagnosed her hole life. We have all the same symptoms but she died before I was diagnosed.
I have lupus. I am on disability for it mostly because of the neuropsychiatric issues. It took 35 years for them to diagnose me and it was the doctors who figured it out, it was because of my own investigations. When I look at these drugs I asked them "can I do the same with diet and environmental changes", they said no. I proved them wrong. I still have flare ups and they are sometimes unpredictable. Just three days ago I had a psychotic episode from COVID, and stress can set me off as well, but the constant pain is not there and my WBC is up and my panels are usually negative.
The biggest problem my mother and I had was that we had neuropsychiatric lupus which meant they they only saw the mental illness and refused to look at other issues. I had constant low WBC, hyperkalemia, leukopenia, discoid lupus, and arthritis but all they ever saw was the metal illness.
So I mostly proved them wrong. For most people with Lupus, it can be overcome with diet and environmental changes.
So, back to the article. I hate articles like this. Lupus is a highly polygenic disease. I have my genetics, I have some SNPs in TLR7 gene at ~10% for europeans. But I feel my Lupus is mostly caused by several purine nucleoside phosphorylase (PNP) SNPs.
https://pubmed.ncbi.nlm.nih.gov/28859258/ https://pubmed.ncbi.nlm.nih.gov/28859258/
But it does not end there, I see STAT4, IL10RB, TNFAIP3 and mutations that probably play a role.
But how is it my diet can negate all these SNPs? Why do some people with these SNPs not get Lupus.
For me, this is where diet and my FADS1 and FAD2 genes play a role. Ever since I started eating only fish and shellfish, and zero plant oils but for some olive oil I have been way more stable than any drug they gave me.
https://www.lupus.org/news/study-shows-omega3-fatty-acid-supplementation-linked-to-reduced-inflammation-and-flaring-in https://www.lupus.org/news/study-shows-omega3-fatty-acid-sup...
I thought being vegan would help when I was younger but it made me worse.
So while that kid is interesting it makes it seem like there is nothing the rest of us can do who do not have these rare point mutations. TLR7 mutations do not cause every case of Lupus.