In general, stuff just works. The most problematic I'm aware of is Microsoft Windows, particularly 3.11 for Workgroups. These days it works, but it still needs

In general, stuff just works. The most problematic I'm aware of is Microsoft Windows, particularly 3.11 for Workgroups. These days it works, but it still needs a patched kernel AIUI. There are APIs in the kernel / memory manager that back then were not public (documented) and are only used by Microsoft themselves.