Absolutely, there were IRQ & DMA defaults that usually worked pretty well in my experience, and in my friend group everybody had memorized fallback combinations

Absolutely, there were IRQ & DMA defaults that usually worked pretty well in my experience, and in my friend group everybody had memorized fallback combinations to try. You never knew when you'd suddenly need to change that stuff when visiting a friend's house. It's funny you mention using your Yamaha keyboard for MIDI out. I did this with the SB Live back in the day, it had a pretty cool front I/O panel too. I remember playing Phantasmagoria this way and getting creeped out really fast. Probably didn't help that the music was coming from my keyboard which was in another part of the room.