3 ms·

Good to hear! Glycine 3 gram before sleep can be useful as a combination. it relaxes the body too and relaxe the mind also. There are interesting studies showin

Good to hear! Glycine 3 gram before sleep can be useful as a combination. it relaxes the body too and relaxe the mind also. There are interesting studies showing positive effects on sleep and no tolerance. magnesium l threonate before sleep, the lthreonate variant penetarte the brain far more than regular magnesium, and it acts as a mild NMDA antagonist, which means it decrease maximal excitation. it is also a great synaptotrophic.

voldacar 4y ago
> the lthreonate variant penetarte the brain far more than regular magnesium How is this possible? Don't the magnesium ions fully dissociate once they come in contact with water, so that there's just free floating Mg+ and threonate?
- SemanticStrengh 4y ago
  > How is this possible? I don't know, that's a good question I somehow the bond must mostly break in the brain but I don't know why. I have made extensive research on magnesiusm forms in the past, there was a great study comparing the amount of magnesium that crossed the blood brain barrier per form. Between a form and another the difference had a lot of variation. Magnesium taurate (not threonate) was the one with the highest crossing. however this study included all forms except threonate.. threonate is known to cross the brain much more than the others and it shows in studies, the effect on synaptogenesis/ gained IQ points is huge and incomparable with other forms. The unknown is how threonate and taurate compare. I'm not aware of comparative studies for threonate but you can see e.g. https://pubmed.ncbi.nlm.nih.gov/31806980/ https://pubmed.ncbi.nlm.nih.gov/31806980/ for absolute values. As to why? I don't know.