5 ms·

Emoxypine doesn't seem to have any English studies, or has incredibly few. So it may or may not be useful, but I sure as heck can't tell.

by rhexs 4y ago

SemanticStrengh 4y ago
here's 438 studies for you https://pubmed.ncbi.nlm.nih.gov/?term=Emoxypine&sort=date https://pubmed.ncbi.nlm.nih.gov/?term=Emoxypine&sort=date the marketing name is mexidol. Emoxypine is a wonder drug for health, it is one of the most potent superoxide antioxidant and has an incredible range of body protective effetcs see e.g. https://en.wikipedia.org/wiki/Emoxypine#Mechanism_of_action https://en.wikipedia.org/wiki/Emoxypine#Mechanism_of_action look at the pictures and admire the amount of saved brain volume https://www.researchgate.net/publication/221738761_Evaluation_of_Effects_of_Histochrome_and_Mexidol_on_Structural_and_Functional_Characteristics_of_the_Brain_in_Senescence-Accelerated_OXYS_Rats_by_Magnetic_Resonance_Imaging https://www.researchgate.net/publication/221738761_Evaluatio...
- rhexs 4y ago
  Interesting. What's the quality of Russian medical research versus western? What journals are considered prestigious? (Not trying to troll -- I honestly have no idea and can't judge it accurately).
  - SemanticStrengh 4y ago
    I have much more respect for russian papers in pharmacology in general than for your average american study. There are many reasons to this: 1) a lot of their research is public. They don't have broken incentives, e.g. they can study the tech that the body use, such as peptides. Big pharma can't leverage endogenous peptides because they're not patentable, a true tragedy that considerably sets back medecine progress. 2) they study outside of the boxe things, they are not afraid to do human trials, they have expertise in gerontology (oxidative stress, bioenergetics, etc) which are often very lacking in american studies. also, those russian researches are generally validated by non-russian working groups. as an example, many of the favorites nootropics people experience have been discovered in russia (racetams, bromantane, etc)
    - rhexs 4y ago
      Thanks, interesting to get this perspective. I have seen a lot of interesting research chemicals and nootropics redditors are using, most of which are prescription drugs in Russia (semax, selank, probably others). Shame there doesn't seem to be any pharmaceutical crossover, would love to see some studies done in the West. I'd be too scared to experiment on myself.
  - PragmaticPulp 4y ago
    > What's the quality of Russian medical research versus western? Generally speaking - not great. There are some interesting Russian compounds out there that seem to do something, but they always fall way short of the miraculous effects shown in old Russian studies. Old Russian pharmaceuticals have actually been a gold mine for supplement sellers in the past two decades because they're basically unregulated pharmaceuticals that can be marketed in the United States and other countries while pointing customers to questionable Russian studies to promote them. If you browse Nootropics forums, you can find scores of people who tried the various compounds. Few people seem to continue any of them for very long either due to lack of primary effects or growing side effects. As I said, the Russian studies paint a very optimistic picture of the drugs. Look at it this way: If any of these old compounds were really miracle drugs, the big pharmaceutical companies would be rushing to get them to market in the United States with some creative patented exclusivity. But none of them have taken any of these compounds past the early research phases. Similar story in other countries. Some potentially interesting compounds, but you have to take the studies with a huge grain of salt.

Emoxypine doesn't seem to have any English studies, or has incredibly few. So it may or may not be useful, but I sure as heck can't tell.

by rhexs 4y ago

Emoxypine doesn't seem to have any English studies, or has incredibly few. So it may or may not be useful, but I sure as heck can't tell.

SemanticStrengh 4y ago

here's 438 studies for you https://pubmed.ncbi.nlm.nih.gov/?term=Emoxypine&sort=date https://pubmed.ncbi.nlm.nih.gov/?term=Emoxypine&sort=date the marketing name is mexidol. Emoxypine is a wonder drug for health, it is one of the most potent superoxide antioxidant and has an incredible range of body protective effetcs see e.g. https://en.wikipedia.org/wiki/Emoxypine#Mechanism_of_action https://en.wikipedia.org/wiki/Emoxypine#Mechanism_of_action look at the pictures and admire the amount of saved brain volume https://www.researchgate.net/publication/221738761_Evaluation_of_Effects_of_Histochrome_and_Mexidol_on_Structural_and_Functional_Characteristics_of_the_Brain_in_Senescence-Accelerated_OXYS_Rats_by_Magnetic_Resonance_Imaging https://www.researchgate.net/publication/221738761_Evaluatio...

rhexs 4y ago
Interesting. What's the quality of Russian medical research versus western? What journals are considered prestigious? (Not trying to troll -- I honestly have no idea and can't judge it accurately).
- SemanticStrengh 4y ago
  I have much more respect for russian papers in pharmacology in general than for your average american study. There are many reasons to this: 1) a lot of their research is public. They don't have broken incentives, e.g. they can study the tech that the body use, such as peptides. Big pharma can't leverage endogenous peptides because they're not patentable, a true tragedy that considerably sets back medecine progress. 2) they study outside of the boxe things, they are not afraid to do human trials, they have expertise in gerontology (oxidative stress, bioenergetics, etc) which are often very lacking in american studies. also, those russian researches are generally validated by non-russian working groups. as an example, many of the favorites nootropics people experience have been discovered in russia (racetams, bromantane, etc)
  - rhexs 4y ago
    Thanks, interesting to get this perspective. I have seen a lot of interesting research chemicals and nootropics redditors are using, most of which are prescription drugs in Russia (semax, selank, probably others). Shame there doesn't seem to be any pharmaceutical crossover, would love to see some studies done in the West. I'd be too scared to experiment on myself.
- PragmaticPulp 4y ago
  > What's the quality of Russian medical research versus western? Generally speaking - not great. There are some interesting Russian compounds out there that seem to do something, but they always fall way short of the miraculous effects shown in old Russian studies. Old Russian pharmaceuticals have actually been a gold mine for supplement sellers in the past two decades because they're basically unregulated pharmaceuticals that can be marketed in the United States and other countries while pointing customers to questionable Russian studies to promote them. If you browse Nootropics forums, you can find scores of people who tried the various compounds. Few people seem to continue any of them for very long either due to lack of primary effects or growing side effects. As I said, the Russian studies paint a very optimistic picture of the drugs. Look at it this way: If any of these old compounds were really miracle drugs, the big pharmaceutical companies would be rushing to get them to market in the United States with some creative patented exclusivity. But none of them have taken any of these compounds past the early research phases. Similar story in other countries. Some potentially interesting compounds, but you have to take the studies with a huge grain of salt.