3 ms·
And not blocking inflammation can kill you. https://www.cancertherapyadvisor.com/home/news/conference-coverage/american-society-of-hematology-ash/ash-2021/ash-
by msla 4y ago
And not blocking inflammation can kill you.
https://www.cancertherapyadvisor.com/home/news/conference-coverage/american-society-of-hematology-ash/ash-2021/ash-2021-car-t-in-depth/anakinra-prevent-severe-crs-icans-car-t-cell-therapy/ https://www.cancertherapyadvisor.com/home/news/conference-co...
CAR T-cell therapy is for refractory or relapsed lymphomas. One of its side-effects is cytokine release syndrome (CRS), an inflammatory response which, in its most severe grade, is fatal. Anakinra, used for rheumatoid arthritis among other things, greatly reduces the severity of CRS in poor yahoos like me receiving CAR T-cell therapy, turning what could be a rocketship ride to Hell into what will more likely be a rather uncomfortable United flight to Newark.
- a1445c8b 4y agoWe probably need to qualify your claim with this phrase taken from the same quote: > in its most severe grade I will hazard a guess that most inflammation is not severe but our tolerance for it has diminished due, in part, to the prevalence of anti-inflammatory drugs.
- teeray 4y agoI think like many things in life, the answer lies somewhere in between. You want inflammation—-just enough, not too much.
- bawolff 4y agoIn other words, it is like literally every other bodily process in existence.
- colechristensen 4y agoIf a treatment can't seriously harm you when overdone, it probably isn't doing anything at all (because it's probably doing nothing).