You don't need any of those tools. One can use virtualenvs to avoid global Python pollution, but that's it. I've used poetry, pipenv and others... Nowadays my

You don't need any of those tools. One can use virtualenvs to avoid global Python pollution, but that's it. I've used poetry, pipenv and others... Nowadays my opinion is that I want my package managers to be simple. For each app, I mantain requirements.txt, requirements.dev.txt, requirements.test.txt... I edit those files manually and only use pip freeze for pinning requirements.freeze.txt For libs, flit + pyproject.toml is a breeze.