This reminds me of Weinstein’s theory that cellular regeneration and cancer are two sides of the same coin. Senescence acts as a last resort against uncontrolle

This reminds me of Weinstein’s theory that cellular regeneration and cancer are two sides of the same coin. Senescence acts as a last resort against uncontrolled mitosis, ie cancer. This is why for example a mole that grows round and stops isn’t worrisome, but one that starts growing again from an arbitrary point and is thus asymmetric is very worrisome. In the former case the would-be tumor has burned out its telomeres and can’t grow anymore. In the latter case it indicates that the telomeric failsafe has failed and that tumor will grow without bound.