4 ms·

I think you're purposefully misrepresenting what "works" means in this context. ADHD people can think a lot more clearly with it. The effect of stimulants is co

I think you're purposefully misrepresenting what "works" means in this context. ADHD people can think a lot more clearly with it. The effect of stimulants is completely different on a brain like ours compared to a normal person as it helps regulates brain function in a way that ours can't. For normal people it just gets you euphoric and agitated, we get CALMER cause we live in a state of constant agitation.

kragen 4y ago
It's not completely different or even mostly different. Getting euphoric and agitated happens with doses an order of magnitude higher than therapeutic doses. Low-dose Adderall has been used to help neurotypical people focus for at least a century, though not of course by that name. Your vicious, baseless attack on my integrity has no place here. Withdraw it immediately.
- luckydata 4y ago
  I'm even more convinced now than before that you're in bad faith.
  - kragen 4y ago
    In https://news.ycombinator.com/item?id=31243297 https://news.ycombinator.com/item?id=31243297 I caught you outright lying about what the relevant studies said, I suppose in hopes that other people wouldn't read them. Your accusations of bad faith are groundless and have no place here. That kind of conduct does not belong on this site.
astrange 4y ago
It really isn't completely different. It does all these things in all people, the difference just being which dose is right for you. I think this was made up to stop it from getting banned entirely like it is in Asia.
- chrsig 4y ago
  citation?
  - kragen 4y ago
    Jesus fuck. Spencer RC, Devilbiss DM, Berridge CW (June 2015). "The Cognition-Enhancing Effects of Psychostimulants Involve Direct Action in the Prefrontal Cortex". Biological Psychiatry. 77 (11): 940–950. doi:10.1016/j.biopsych.2014.09.013. PMC 4377121. PMID 25499957. Ilieva IP, Hook CJ, Farah MJ (June 2015). "Prescription Stimulants' Effects on Healthy Inhibitory Control, Working Memory, and Episodic Memory: A Meta-analysis". Journal of Cognitive Neuroscience. 27 (6): 1069–1089. doi:10.1162/jocn_a_00776. PMID 25591060. S2CID 15788121. Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 13: Higher Cognitive Function and Behavioral Control". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, USA: McGraw-Hill Medical. pp. 318, 321. ISBN 9780071481274 Bagot KS, Kaminer Y (April 2014). "Efficacy of stimulants for cognitive enhancement in non-attention deficit hyperactivity disorder youth: a systematic review". Addiction. 109 (4): 547–557. doi:10.1111/add.12460. PMC 4471173. PMID 24749160. Wood S, Sage JR, Shuman T, Anagnostaras SG (January 2014). "Psychostimulants and cognition: a continuum of behavioral and cognitive activation". Pharmacological Reviews. 66 (1): 193–221. doi:10.1124/pr.112.007054. PMC 3880463. PMID 24344115. Teter CJ, McCabe SE, LaGrange K, Cranford JA, Boyd CJ (October 2006). "Illicit use of specific prescription stimulants among college students: prevalence, motives, and routes of administration". Pharmacotherapy. 26 (10): 1501–1510. doi:10.1592/phco.26.10.1501. PMC 1794223. PMID 16999660.
    - luckydata 4y ago
      a quick scan of the papers you linked (top 2 results, I got bored after that) shows that the studies specifically refer to ADHD patients. I'm not sure the links prove the point you're trying to make. Tangentially related, interesting tidbit from Russel Barkley: https://www.youtube.com/watch?v=HYq571cycqg https://www.youtube.com/watch?v=HYq571cycqg TL;DR: stimulants prescribed to children promote normal brain development.

kragen 4y ago

It's not completely different or even mostly different. Getting euphoric and agitated happens with doses an order of magnitude higher than therapeutic doses. Low-dose Adderall has been used to help neurotypical people focus for at least a century, though not of course by that name. Your vicious, baseless attack on my integrity has no place here. Withdraw it immediately.

luckydata 4y ago
I'm even more convinced now than before that you're in bad faith.
- kragen 4y ago
  In https://news.ycombinator.com/item?id=31243297 https://news.ycombinator.com/item?id=31243297 I caught you outright lying about what the relevant studies said, I suppose in hopes that other people wouldn't read them. Your accusations of bad faith are groundless and have no place here. That kind of conduct does not belong on this site.

astrange 4y ago

It really isn't completely different. It does all these things in all people, the difference just being which dose is right for you. I think this was made up to stop it from getting banned entirely like it is in Asia.

chrsig 4y ago
citation?
- kragen 4y ago
  Jesus fuck. Spencer RC, Devilbiss DM, Berridge CW (June 2015). "The Cognition-Enhancing Effects of Psychostimulants Involve Direct Action in the Prefrontal Cortex". Biological Psychiatry. 77 (11): 940–950. doi:10.1016/j.biopsych.2014.09.013. PMC 4377121. PMID 25499957. Ilieva IP, Hook CJ, Farah MJ (June 2015). "Prescription Stimulants' Effects on Healthy Inhibitory Control, Working Memory, and Episodic Memory: A Meta-analysis". Journal of Cognitive Neuroscience. 27 (6): 1069–1089. doi:10.1162/jocn_a_00776. PMID 25591060. S2CID 15788121. Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 13: Higher Cognitive Function and Behavioral Control". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, USA: McGraw-Hill Medical. pp. 318, 321. ISBN 9780071481274 Bagot KS, Kaminer Y (April 2014). "Efficacy of stimulants for cognitive enhancement in non-attention deficit hyperactivity disorder youth: a systematic review". Addiction. 109 (4): 547–557. doi:10.1111/add.12460. PMC 4471173. PMID 24749160. Wood S, Sage JR, Shuman T, Anagnostaras SG (January 2014). "Psychostimulants and cognition: a continuum of behavioral and cognitive activation". Pharmacological Reviews. 66 (1): 193–221. doi:10.1124/pr.112.007054. PMC 3880463. PMID 24344115. Teter CJ, McCabe SE, LaGrange K, Cranford JA, Boyd CJ (October 2006). "Illicit use of specific prescription stimulants among college students: prevalence, motives, and routes of administration". Pharmacotherapy. 26 (10): 1501–1510. doi:10.1592/phco.26.10.1501. PMC 1794223. PMID 16999660.
  - luckydata 4y ago
    a quick scan of the papers you linked (top 2 results, I got bored after that) shows that the studies specifically refer to ADHD patients. I'm not sure the links prove the point you're trying to make. Tangentially related, interesting tidbit from Russel Barkley: https://www.youtube.com/watch?v=HYq571cycqg https://www.youtube.com/watch?v=HYq571cycqg TL;DR: stimulants prescribed to children promote normal brain development.