3 ms·

I have been diagnosed with ADHD as a young child and it has been extremely difficult to deal with it . Now I have tried many of the usual stimulants and luckily

I have been diagnosed with ADHD as a young child and it has been extremely difficult to deal with it . Now I have tried many of the usual stimulants and luckily they do actually work! The problem I have is the side effects. They give me strong and I mean super strong anxiety which negatively affects my life and social life in every way. From my experience with asking other people and professionals, this seems to be extremely rare and they don't have the same problems with the same medication. I really wish I lived a few years into the future where maybe a medication that is suitable for me exists :(

SemanticStrengh 5y ago
The medication you're waiting for will not come in the future, either I mentionned it in my comment either it doesn't exist. Chances are moclobemide or (I'd try first) selegiline would be a better feat for u. As I said the drugs I mention can be used not necessarily to replace but to lower your stimulant dosage and therefore anxiety. As for the anxiety it can itself be mitigated, by taking low dose clonidine (slighly sedating) or guanfacine (less sedating), and they can be bought OTC. Many people report magnesium-l-threonate reduce stimulant anxietu (which is logic since it is a weak NMDA antagonist). If you want more strong solution against stim anxiety, either use a potent NMDA antagonist like low dose memantine (cause brain fog the first weeks) or use a low dose beta-blocker (some again being OTC) Also vyvanse cause less anxiety than adderall. As I said, zinc supplementation can reduce your adderal dose by 1/third and hence side effects. There are also mild efficacy blunters, such as l-theanine, pine bark extract (promising) or ginkgo biloba. If the stress is due to vasocontrition you might wanna try cialis. then there are atypical non-addictive anxiolytics (afobazole, opipramol, etifoxine (beware liver monitoring), emoxypine, tofisopam)
- sureglymop 5y ago
  Thank you for your comment, for the insight and ! It's been extremely hard to basically "debate" or "convince" my psychiatrist that Ritalin and Vyvanse make my anxiety so much worse. I also want to mention that I'm in my 20s so I've been scared that taking a "cocktail of medication" might affect my life in the future. My psychiatrist has basically been trying to convince me that I should have more self-esteem, should reduce stressful situations and that when it comes to medication there are no other options. I will bring up your suggestions in my next session.
  - SemanticStrengh 5y ago
    Sorry but you don't get it. Your psychiatrist has not the scientific knowledge required, by far. He has never heard of any of the drug I mentioned and most of them are not officially prescribed for those uses anyway. For anxiety though at least in the U.S he could prescribe guanfacine, which improve both adhd and reduce anxiety. So yeah talk about guanfacine or else the inferior clonidine. Magnesium l threonate is a benign supplement you can buy online. Memantine is not benign but you can buy it online and find info on reddit. I don't advise the anxiolytics i mentioned for long chronic use although it's technically possible. Emoxypine though is good for health in general. As for Cialis the sex pill, well your psychiatrist will never wanna hear it but by canceling vasoconstriction it will reduce stim toxicity, not increase it. As i said zinc is worth a try but only if it allow reducing the stim dose. Again a benign supplement OTC. I would also consider alcar though less effective it helps reduce toxicity.
burner556 5y ago
Try vyvanse/dexedrine and then if that doesn't work desoxyn/methamphetamine. Both are anti-anxiety for me. Adderall is the worst.
- goshakkk 4y ago
  Can confirm. Desoxyn is the only stimulant that works for me. Other stimulants usually do less in terms of positive effects _and_ have more side effects. Vyvanse was probably my second best so far, though it was still unpleasant and if I didn't land on Desoxyn, I'm not sure I would be putting up with Vyvanse. Adderall was a fucking hell.
- SemanticStrengh 5y ago
  There is a reason why methamphetamine cause less anxiety, it is a mild agonist of the very interesting sigma receptor. You can methamphetamize your adderall/vyanse by taking the effective and well tolerated anxiolytic sigmaergic opipramol, unfortunately very hard to find in europe.
  - burner556 5y ago
    Thanks for your reply. Methamphetamine is top tier adhd treatment. It's a shame it's so stigmatized.
    - SemanticStrengh 5y ago
      Yes, desoxyn is a thing though and 2 fma is legal. BTW there are OTC levo-meth decongestants
- sureglymop 5y ago
  Thank you! I have never tried Adderall, maybe it's not widespread here (I'm in Europe). I have tried Vyvanse and it also made my anxiety worse unfortunately. The thing is that I already have quite some anxiety without the ADHD meds, but with them it gets much worse (even though I can focus better). I will take a look at Desoxyn.

SemanticStrengh 5y ago

The medication you're waiting for will not come in the future, either I mentionned it in my comment either it doesn't exist. Chances are moclobemide or (I'd try first) selegiline would be a better feat for u. As I said the drugs I mention can be used not necessarily to replace but to lower your stimulant dosage and therefore anxiety. As for the anxiety it can itself be mitigated, by taking low dose clonidine (slighly sedating) or guanfacine (less sedating), and they can be bought OTC. Many people report magnesium-l-threonate reduce stimulant anxietu (which is logic since it is a weak NMDA antagonist). If you want more strong solution against stim anxiety, either use a potent NMDA antagonist like low dose memantine (cause brain fog the first weeks) or use a low dose beta-blocker (some again being OTC) Also vyvanse cause less anxiety than adderall. As I said, zinc supplementation can reduce your adderal dose by 1/third and hence side effects. There are also mild efficacy blunters, such as l-theanine, pine bark extract (promising) or ginkgo biloba. If the stress is due to vasocontrition you might wanna try cialis. then there are atypical non-addictive anxiolytics (afobazole, opipramol, etifoxine (beware liver monitoring), emoxypine, tofisopam)

sureglymop 5y ago
Thank you for your comment, for the insight and ! It's been extremely hard to basically "debate" or "convince" my psychiatrist that Ritalin and Vyvanse make my anxiety so much worse. I also want to mention that I'm in my 20s so I've been scared that taking a "cocktail of medication" might affect my life in the future. My psychiatrist has basically been trying to convince me that I should have more self-esteem, should reduce stressful situations and that when it comes to medication there are no other options. I will bring up your suggestions in my next session.
- SemanticStrengh 5y ago
  Sorry but you don't get it. Your psychiatrist has not the scientific knowledge required, by far. He has never heard of any of the drug I mentioned and most of them are not officially prescribed for those uses anyway. For anxiety though at least in the U.S he could prescribe guanfacine, which improve both adhd and reduce anxiety. So yeah talk about guanfacine or else the inferior clonidine. Magnesium l threonate is a benign supplement you can buy online. Memantine is not benign but you can buy it online and find info on reddit. I don't advise the anxiolytics i mentioned for long chronic use although it's technically possible. Emoxypine though is good for health in general. As for Cialis the sex pill, well your psychiatrist will never wanna hear it but by canceling vasoconstriction it will reduce stim toxicity, not increase it. As i said zinc is worth a try but only if it allow reducing the stim dose. Again a benign supplement OTC. I would also consider alcar though less effective it helps reduce toxicity.

burner556 5y ago

Try vyvanse/dexedrine and then if that doesn't work desoxyn/methamphetamine. Both are anti-anxiety for me. Adderall is the worst.

goshakkk 4y ago
Can confirm. Desoxyn is the only stimulant that works for me. Other stimulants usually do less in terms of positive effects _and_ have more side effects. Vyvanse was probably my second best so far, though it was still unpleasant and if I didn't land on Desoxyn, I'm not sure I would be putting up with Vyvanse. Adderall was a fucking hell.
SemanticStrengh 5y ago
There is a reason why methamphetamine cause less anxiety, it is a mild agonist of the very interesting sigma receptor. You can methamphetamize your adderall/vyanse by taking the effective and well tolerated anxiolytic sigmaergic opipramol, unfortunately very hard to find in europe.
- burner556 5y ago
  Thanks for your reply. Methamphetamine is top tier adhd treatment. It's a shame it's so stigmatized.
  - SemanticStrengh 5y ago
    Yes, desoxyn is a thing though and 2 fma is legal. BTW there are OTC levo-meth decongestants
sureglymop 5y ago
Thank you! I have never tried Adderall, maybe it's not widespread here (I'm in Europe). I have tried Vyvanse and it also made my anxiety worse unfortunately. The thing is that I already have quite some anxiety without the ADHD meds, but with them it gets much worse (even though I can focus better). I will take a look at Desoxyn.