It depends. If you use software with many years of stability, it's safe (Bitcoin has a 9 year uptime). There are some very reputable companies, like Casa or Unc

It depends. If you use software with many years of stability, it's safe (Bitcoin has a 9 year uptime). There are some very reputable companies, like Casa or Unchained Capita that help you store your money safely using multisig contracts and hardware wallets very safely without trust in them. With newer, faster changing software of course the risk is much higher, so I'm not comfortable using them, but many people take that risk.