Well, we haven't optimized away bacteria, or mice, or fleas. Plants can't run or fight us directly, yet we haven't gotten rid of them. We put a lot of effort in

Well, we haven't optimized away bacteria, or mice, or fleas. Plants can't run or fight us directly, yet we haven't gotten rid of them. We put a lot of effort into attacking particular pathogens like COVID-19, HIV, and many others, but it's a tiny fraction of the things out there that catch our attention. And on the other end of the scale, various large animals in Africa seem to have evolved with humans to be extremely mean and dangerous, so they didn't go extinct quickly like megafauna elsewhere. It makes sense that AGI will profoundly change humans, but to me, not so much that it will suddenly wipe us out the way perhaps humans wiped out woolly mammoths or the like. Because we won't be isolated from it while it is developing.