I hosted my own email for years and had no real issues. The only reason I stopped was that my main motivation for self-hosting was security, and there are now

I hosted my own email for years and had no real issues. The only reason I stopped was that my main motivation for self-hosting was security, and there are now providers (ProtonMail, FastMail, et al) that are reasonable options to solve for my needs and require no maintenance effort on my part. My experience has been that all the major providers will deliver mail if it's appropriately signed with DKIM and you have proper SPF records, as long as you aren't originating from an IP that has a low reputation score. The biggest challenge is getting a clean IP, since there is limited IPv4 address space and most IPs have been recycled so much at this point that they all have low reputation scores. The best way to get an IP with a good reputation score is to host on physical hardware, not on VMs, with a smaller provider that has minimal customer churn.