I don't know if there really has been a clinically relevant antibiotic with actual use in the real world discovered in the last 20 years in such circu

I don't know if there really has been a clinically relevant antibiotic with actual use in the real world discovered in the last 20 years in such circumstances. It's difficult to know if this is because we've exhausted nature's supply of antibiotics, or if we haven't found any because we haven't been looking. Over the past 10-20 years there have been many articles about how pharma companies have largely abandoned the quest for better antibiotics in favor of more profitable lines of medicine. As a total outsider, I have no way to judge which one is true.