4 ms·

What benefits were they measuring in this study? I’d be curious to look at biological age markers, inflammation, autophagy, maybe improvements in insulin respo

• vannevar 4y ago
  From the original paper: "Results of analyses of waist circumferences, BMI, body fat, body lean mass, blood pressure, and metabolic risk factors were consistent with the results of the primary outcome. In addition, there were no substantial differences between the groups in the numbers of adverse events." So weight loss was the primary target, with some ancillary metrics. But it was only a 12-month baseline, which may not show longer-term benefits. And it didn't include any effort to assess things like inflammation or immune system robustness, which personally are the only reasons I do intermittent fasting.