3 ms·

I’d imagine there are quite a few studies that say the opposite? Is this study special? Larger sample size?

• tokai 4y ago
  Looking at a review[0] on TRE from 2020 it says: >The studies to date in humans are limited in size and duration, and the effectiveness and acceptability of TRE in the general population remains unclear. Skimming this new paper and it seems to me that the sample size is about twice as big as previous studies. [0] https://www.sciencedirect.com/science/article/pii/S2589004220303461?via%3Dihub https://www.sciencedirect.com/science/article/pii/S258900422...
• karpierz 4y ago
  Other studies don't control for the amount being eaten. Time-restricted eating is a technique for eating less food, but aside from that it doesn't have intrinsic benefits.
  • mrfusion 4y ago
    What benefits were they measuring in this study? I’d be curious to look at biological age markers, inflammation, autophagy, maybe improvements in insulin response, cardiovascular health in the long term.
    • vannevar 4y ago
      From the original paper: "Results of analyses of waist circumferences, BMI, body fat, body lean mass, blood pressure, and metabolic risk factors were consistent with the results of the primary outcome. In addition, there were no substantial differences between the groups in the numbers of adverse events." So weight loss was the primary target, with some ancillary metrics. But it was only a 12-month baseline, which may not show longer-term benefits. And it didn't include any effort to assess things like inflammation or immune system robustness, which personally are the only reasons I do intermittent fasting.