If it's to be recommended for NHS use it can't cost anything like that to us; the maximum threshold for NICE is normally something like £20k-£30k per Quality Ad

If it's to be recommended for NHS use it can't cost anything like that to us; the maximum threshold for NICE is normally something like £20k-£30k per Quality Adjusted Life Year. Interestingly, it looks like it hasn't had a NICE recommendation yet, and is currently proceeding under some kind of interim data-gathering agreement (which looks like a political fudge of the cost effectiveness guideline). The BNF is giving an indicative price of £8346.30 for a month's supply (plus presumably another £7000 for the accompanying ivacaftor alone). Of course, the patient will pay effectively nothing (a prescription prepayment certificate is only £108.10 for 12 months!) [0]: https://bnf.nice.org.uk/medicinal-forms/tezacaftor-with-ivacaftor-and-elexacaftor.html https://bnf.nice.org.uk/medicinal-forms/tezacaftor-with-ivac...