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The same protein can deform into multiple different 3D shapes, called conformations. Some proteins are rigid and exist almost exclusively in a single conformati
by jostmey 5y ago
The same protein can deform into multiple different 3D shapes, called conformations. Some proteins are rigid and exist almost exclusively in a single conformation. It is probably easier to determine the 3D structure of proteins with a single, dominant conformation. Other proteins don't have well defined conformations, and are more like a tangle of rope that can bend in many different ways
- panabee 5y agothanks for the explanation. what are the biggest factors influencing conformation? what are the best ways today for imaging proteins with different conformations, and what are the limitations of these methods?