"I think other studies have used Nicotine and other substances to provide an initial flush of feeling like you took something." Niacin, not nicotine. See the

"I think other studies have used Nicotine and other substances to provide an initial flush of feeling like you took something." Niacin, not nicotine. See the so-called "niacin-flush" response: https://en.wikipedia.org/wiki/Niacin#Flushing https://en.wikipedia.org/wiki/Niacin#Flushing