Speaking as someone with direct experience maintaining Access databases that should have been SQL Server from inception, yes it absolutely does. If you need to

Speaking as someone with direct experience maintaining Access databases that should have been SQL Server from inception, yes it absolutely does. If you need to force feed 10+GB through Access artificial 2GB constraint and your programming language (VBA) is both single threaded and interpreted, if you aren't clever then you will run into performance problems, just as you would if you were doing something similar in Javascript or Python + SQLite.