If humans were at peak fitness, I think there would be more promise in this hypothesis. But with the explosion of health issues like obesity and heart failure,

If humans were at peak fitness, I think there would be more promise in this hypothesis. But with the explosion of health issues like obesity and heart failure, confounded by everything from diet to endocrine disruption, it's hard to conclude that we should be leaving stones unturned. Also, longevity is only one metric. End-to-end quality of life seems to be more revealing to me about the state of our health, not just how long medicine can prop us up despite our issues. For example, why are 26% of men under 40 suffering from erectile disfunction? Why are more people on medications for mental health? etc. To what extent does any part of the system, including microplastics, impact these issues?