Theoretically, screen readers handle the "semantic web" better than anything else. Divs are used for layout and presentation, and don't convey much useful infor

Theoretically, screen readers handle the "semantic web" better than anything else. Divs are used for layout and presentation, and don't convey much useful information about structure most of the time, so div-heavy sites can be really hard for blind people even if they look great, clean, minimal, and simple for the sighted. I say "theoretically" because I'm not blind and have never used a screen reader, and I'm not extremely experienced in the area.