https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985449/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985449/ https://www.vice.com/en/article/pkeqd8/what-happens-

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985449/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985449/ https://www.vice.com/en/article/pkeqd8/what-happens-lsd-overdose https://www.vice.com/en/article/pkeqd8/what-happens-lsd-over... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289311/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289311/ TLDR Its thought LSD sort of mimics SSRI's and locks into the serotonin receptor, but which receptor I dont know as I havent read the article and there will be a few different one's if other receptors are to go by, like histamine. SSRI's can affect your sleep which will affect your memories and possibly your work. If you program then not being able to remember where code is could be a problem but it might not be. Escitalopram is like doing Ecstasy (MDMA) if you drink copious amounts of black tea and sugar when on them, ie you will have little E rushes throughout the day which could send your life off the rails. Melatonin besides being the sleep hormone is an anti oxidant and helps release stem cells and SSRI's can affect this hormone. The older MAOI's maybe better, but OD on those and you will literally lights out and have no recollection of passing out. Popular with those looking to end it which is why SSRI's came to be. Problem with some of the SSRI's is they can also affect other parts of the brain which could heighten aggression and other less than desirable effects. You will reports of some SSRI's even on here https://www.erowid.org/pharms/fluoxetine/fluoxetine.shtml https://www.erowid.org/pharms/fluoxetine/fluoxetine.shtml I'd also look into the metals that make up various SOD's. Super Oxide Dismutase's they reduces Free Radicals and these can contribute enormously to stress, and other less than desirable effects in the body. Start with copper. An inorganic Carbonate would probably be the only form of a metal I'd touch not chloride & sulfate, the others I would get chelated ie a metal bound to something like Glycine, which causes vasodilation and reduces inflammation , and happens to be the one chemical that has significantly increased the life span of rats more than anything else. It powers up the mitochondria. I'd take a serious look at your diet though, your environment and even your sleep habits. Identify what it is that gets you down and see if you can resolve them. Easier said than down when considering how stubborn or criminal people can be which may be contributing your depression, but I'd start with diet and environment, and I'm not qualified in anything except my own opinion!