I'm a nobody but I'll tell you a small experience I had with Pyramid (/ Pylons) - it didn't do too much for you in terms of admin UIs and things like Django etc

I'm a nobody but I'll tell you a small experience I had with Pyramid (/ Pylons) - it didn't do too much for you in terms of admin UIs and things like Django etc but one thing it did really well is make a lot of its decisions easy to override. It uses the much-maligned Zope Component Architecture, but in practice it meant most parts of it could be switched out when you needed different functionality. (random mixing of past and present tense because it's still around and presumably still good but I don't use it)