4 ms·

I wonder how this would look if we consider LDL, HDL and triglycerides individually... Perhaps that would be more telling than just considering total cholestero

by osrec 5y ago

I wonder how this would look if we consider LDL, HDL and triglycerides individually... Perhaps that would be more telling than just considering total cholesterol.

Terry_Roll 5y ago
Diet is also a factor. Nicotinic Acid (vitamin B3) will lower Cholesterol because it converts cholesterol into hormones starting with Pregnenolone, 500mg of nicotinic acid on an empty stomach or fat free meal is the fastest cheapest way to get a growth hormone boost, if you can handle the prostaglandin 9sun burn) flush! https://en.wikipedia.org/wiki/Steroid_hormone#/media/File:Steroidogenesis.svg https://en.wikipedia.org/wiki/Steroid_hormone#/media/File:St... Manganese also affects cholesterol. https://pubmed.ncbi.nlm.nih.gov/3705654/ https://pubmed.ncbi.nlm.nih.gov/3705654/ "a favourable influence of manganese was shown which effected a decrease of the cholesterol content of serum, liver and aorta and inhibited the entry of lipids into the aorta. The influence of the manganese on various enzymes as well as a manganese-copper interaction are discussed as possible causes." Manganese is one of those minerals in constant decline from birth when Reactive Oxygen Species starts, before then we all get about 9months to build up levels in the body, provided the mother is healthy and has an healthy diet. And there isnt much discussion on the content of HDL. https://en.wikipedia.org/wiki/High-density_lipoprotein#Overview https://en.wikipedia.org/wiki/High-density_lipoprotein#Overv... And on the point of macrophage accumulation, no mention of how vit K1 keeps calcium out of tissue which prevents elastic fibres from hardening and thus causing their own problems. Thing is whatever science looks at can be portrayed in a positive or negative light.
- awiesenhofer 5y ago
  The part about B3 sounds very interesting but whats a prostaglandin flush?
  - johncearls 5y ago
    Your skin turns read and feels hot, like a sunburn. It's the number one side effect of high dose niacin. There are some prescription extended release prescription niacins to reduce that effect, but it still happens. It's very uncomfortable, which is a real problem for something you take daily.
    - Terry_Roll 5y ago
      niacinamide (the amide form is post chemical reaction). https://en.wikipedia.org/wiki/Niacin#Adverse_effects https://en.wikipedia.org/wiki/Niacin#Adverse_effects https://en.wikipedia.org/wiki/Tryptophan#/media/File:Tryptophan_metabolism.svg https://en.wikipedia.org/wiki/Tryptophan#/media/File:Tryptop... Tryptophan -> 5HTP -> Serotonin Tryptophan -> Nicotinic acid -> Niacinamide One thing they dont mention about nicotinic acid is it will soften your bones possibly because prostaglandins uses calcium inside the cell to rebind DNA. So then it becomes a case of take some K2-mk4 to help repair your bones, and thats when people are forced to explore the chemical pathways inside their bodies to compensate for other effects which perhaps they dont want.
refurb 5y ago
Well, we already have PCSK9 inhibitors, which came about because people with PCSK9 mutations have very low LDL levels as well as very low risk of coronary artery disease. So it appears that you can drive LDL levels quite low without harm. https://en.wikipedia.org/wiki/PCSK9 https://en.wikipedia.org/wiki/PCSK9

by osrec 5y ago

I wonder how this would look if we consider LDL, HDL and triglycerides individually... Perhaps that would be more telling than just considering total cholesterol.

Terry_Roll 5y ago

Diet is also a factor. Nicotinic Acid (vitamin B3) will lower Cholesterol because it converts cholesterol into hormones starting with Pregnenolone, 500mg of nicotinic acid on an empty stomach or fat free meal is the fastest cheapest way to get a growth hormone boost, if you can handle the prostaglandin 9sun burn) flush! https://en.wikipedia.org/wiki/Steroid_hormone#/media/File:Steroidogenesis.svg https://en.wikipedia.org/wiki/Steroid_hormone#/media/File:St... Manganese also affects cholesterol. https://pubmed.ncbi.nlm.nih.gov/3705654/ https://pubmed.ncbi.nlm.nih.gov/3705654/ "a favourable influence of manganese was shown which effected a decrease of the cholesterol content of serum, liver and aorta and inhibited the entry of lipids into the aorta. The influence of the manganese on various enzymes as well as a manganese-copper interaction are discussed as possible causes." Manganese is one of those minerals in constant decline from birth when Reactive Oxygen Species starts, before then we all get about 9months to build up levels in the body, provided the mother is healthy and has an healthy diet. And there isnt much discussion on the content of HDL. https://en.wikipedia.org/wiki/High-density_lipoprotein#Overview https://en.wikipedia.org/wiki/High-density_lipoprotein#Overv... And on the point of macrophage accumulation, no mention of how vit K1 keeps calcium out of tissue which prevents elastic fibres from hardening and thus causing their own problems. Thing is whatever science looks at can be portrayed in a positive or negative light.

awiesenhofer 5y ago
The part about B3 sounds very interesting but whats a prostaglandin flush?
- johncearls 5y ago
  Your skin turns read and feels hot, like a sunburn. It's the number one side effect of high dose niacin. There are some prescription extended release prescription niacins to reduce that effect, but it still happens. It's very uncomfortable, which is a real problem for something you take daily.
  - Terry_Roll 5y ago
    niacinamide (the amide form is post chemical reaction). https://en.wikipedia.org/wiki/Niacin#Adverse_effects https://en.wikipedia.org/wiki/Niacin#Adverse_effects https://en.wikipedia.org/wiki/Tryptophan#/media/File:Tryptophan_metabolism.svg https://en.wikipedia.org/wiki/Tryptophan#/media/File:Tryptop... Tryptophan -> 5HTP -> Serotonin Tryptophan -> Nicotinic acid -> Niacinamide One thing they dont mention about nicotinic acid is it will soften your bones possibly because prostaglandins uses calcium inside the cell to rebind DNA. So then it becomes a case of take some K2-mk4 to help repair your bones, and thats when people are forced to explore the chemical pathways inside their bodies to compensate for other effects which perhaps they dont want.

refurb 5y ago

Well, we already have PCSK9 inhibitors, which came about because people with PCSK9 mutations have very low LDL levels as well as very low risk of coronary artery disease. So it appears that you can drive LDL levels quite low without harm. https://en.wikipedia.org/wiki/PCSK9 https://en.wikipedia.org/wiki/PCSK9