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I don’t think it’s “more important”, without a reference genome it’s impossible to take the next step and the Human Genome Project successfully took us from 0 t
by jahewson 5y ago
I don’t think it’s “more important”, without a reference genome it’s impossible to take the next step and the Human Genome Project successfully took us from 0 to 1. Going from 1 to n is much easier. The Human Pangenome Project is working on this and should have 350 diverse genomes sequenced within the next couple of years.
Note that this has nothing to do with collecting variations in individual genes - that’s easy and widely available. But about collecting variations in the actual content and structure of the genome. e.g. Some populations have a bunch of extra DNA that most other humans lack, amazing.