3 ms·

As someone who personally experienced a rapid and significant resolution of ADHD, fatigue, and other symptoms as a result of a methylation test + methionine su

As someone who personally experienced a rapid and significant resolution of ADHD, fatigue, and other symptoms as a result of a methylation test + methionine supplementation (supervised and recommended by a mainstream medical doctor at my primary care clinic), this is amusing to read. Cue the "but anecdotal experiences aren't valid" hyperbole. > Any test that claims to be relevant to so many different medical conditions is a huge red flag. How much do you understand about DNA methylation? > If you really wanted to test something, you'd skip this test and get a cheap genetic test to see your MTHFR variant (note: heterozygous is fine, no matter what the naturopaths try to tell you). Homozygous C677T still affects ~10% of caucasians but isn't sufficient in and of itself to show poor methylation. C677T only shows a predisposition to the problem. So you have it backwards on recommended tests. Since not everyone knows where to find cheap genetic tests, I'll be a good neighbor and recommend Nebula Genomics + Promethease (with the exported raw data). Stay away from 23andme.

PragmaticPulp 5y ago
I’m glad you found resolution for your personal symptoms with the help of a doctor. The mistake is promoting methylation quackery as the underlying cause of everything, as your link above did. It’s obvious quackery and the medical community unanimously agrees (see my references above). I’m glad you found a specific help for your specific situation. Extending that to be a wide-scale affliction of the population is the mistake. I hope everyone reading this thread takes time to review mainstream medical sources (not naturopathic authors, test peddling websites, or anecdotes)
- celdon25 5y ago
  My guy, the parent commenter has been suffering for decades. It’s not unreasonable to try new ideas at this point, nor is it unreasonable to assume that mainstream medicine has done what it can. The cost of the test is relatively low, and the risks of taking SAMe or L-methionine are low as well. The only risk here is that to the bottom line of the AMA cartel. The test I linked is the same one that I had taken, don’t judge a book by its cover. It’s not a catch all for everything, that’s why I suggested a $200 test, not a $20 supplement. > Extending that to be a wide-scale affliction of the population is the mistake. The very real pandemic of not-my-problem-itis is what led to this, with Obamacare making it into a gasoline fire. Good for profits, bad for life expectancy. > the medical community unanimously agrees (see my references above). The whole premise of that Cleveland Clinic article is based on the idea that genetic testing costs thousands of dollars as it does under the AMA cartel prices. Mayo Clinic for example charges $7000 for a few dozen generic markers. The genetic test I suggested is $99, and you get the entire part of the genome that has variations among humans. I would agree with the article that you shouldn’t pay an arm and a leg for a single genetic marker, but that’s not what we are talking about here.

PragmaticPulp 5y ago

I’m glad you found resolution for your personal symptoms with the help of a doctor. The mistake is promoting methylation quackery as the underlying cause of everything, as your link above did. It’s obvious quackery and the medical community unanimously agrees (see my references above). I’m glad you found a specific help for your specific situation. Extending that to be a wide-scale affliction of the population is the mistake. I hope everyone reading this thread takes time to review mainstream medical sources (not naturopathic authors, test peddling websites, or anecdotes)

celdon25 5y ago
My guy, the parent commenter has been suffering for decades. It’s not unreasonable to try new ideas at this point, nor is it unreasonable to assume that mainstream medicine has done what it can. The cost of the test is relatively low, and the risks of taking SAMe or L-methionine are low as well. The only risk here is that to the bottom line of the AMA cartel. The test I linked is the same one that I had taken, don’t judge a book by its cover. It’s not a catch all for everything, that’s why I suggested a $200 test, not a $20 supplement. > Extending that to be a wide-scale affliction of the population is the mistake. The very real pandemic of not-my-problem-itis is what led to this, with Obamacare making it into a gasoline fire. Good for profits, bad for life expectancy. > the medical community unanimously agrees (see my references above). The whole premise of that Cleveland Clinic article is based on the idea that genetic testing costs thousands of dollars as it does under the AMA cartel prices. Mayo Clinic for example charges $7000 for a few dozen generic markers. The genetic test I suggested is $99, and you get the entire part of the genome that has variations among humans. I would agree with the article that you shouldn’t pay an arm and a leg for a single genetic marker, but that’s not what we are talking about here.